What is the main use of infliximab?

Infliximab is primarily used to manage chronic arthritis, particularly autoimmune forms such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, ankylosing spondylitis, and psoriatic arthritis. This monoclonal antibody works by inhibiting tumor necrosis factor-alpha (TNF-alpha), a substance in the body that leads to inflammation and tissue destruction in these chronic conditions. By blocking TNF-alpha, infliximab helps reduce the inflammatory response, thereby decreasing joint pain and swelling, improving function and quality of life for individuals suffering from chronic arthritis.

In contrast, the other options focus on different health issues not treated by infliximab. For instance, infliximab has no role in the treatment of bone fractures, muscle spasticity, or infections, as it is specifically designed to target inflammatory and immune-mediated conditions.